par Glineur, Régine 
;Louryan, Stéphane ;Philippson, Catherine ;Evrard, Laurence ;De Vos, Louis
Référence European journal of morphology, 36, 4-5, page (245-252)
Publication Publié, 1998-12
;Louryan, Stéphane ;Philippson, Catherine ;Evrard, Laurence ;De Vos, Louis Référence European journal of morphology, 36, 4-5, page (245-252)
Publication Publié, 1998-12
Article révisé par les pairs
| Résumé : | The purpose of this study was to observe the effects of irradiation on the craniofacial development of NMRI mouse embryos. Two populations of pregnant mice were irradiated with a single dose of 2 Gray on day 8 of gestation for the first population (Po. 1) and on day 9 of gestation for the second population (Po. 2). On gestational days 9 to 17, embryos were submitted to histological and scanning electron microscope examinations. The two populations of embryos presented a high percentage of centro-facial hypoplasia (74.7% for Po. 1 and 75% for Po. 2) which was more pronounced in the latter one. Ocular anomalies were present in 16% of the first population. Cases of anencephaly, cleft palate and anomalies of the central nervous system were found in both populations. |
