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MR imaging versus PET/CT for evaluation of pancreatic lesions.

par Belião, Sara;Ferreira, Alexandra;Vierasu, Irina;Blocklet, Didier ;Goldman, Serge ;Metens, Thierry ;Ma, Shuqing
Référence European journal of radiology
Publication Publié, 2011-12

Article révisé par les pairs

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Résumé :

PURPOSE: To retrospectively determine the diagnostic accuracy of magnetic resonance imaging (MRI) and combined positron emission tomography/computed tomography (PET/CT) in the differential diagnosis of benign and malignant pancreatic lesions. MATERIALS AND METHODS: Twenty-seven patients (15 women/12 men, mean age 56.5 years) with MR imaging and PET/CT studies performed to differentiate benign and malignant pancreatic lesions were identified between October 2008 and October 2010. Both MR and PET/CT data sets were retrospectively and blindly evaluated by two independent readers (4 readers total) with different degrees of experience, using a visual five-point score system. The results were correlated with final diagnosis obtained by histopathology. RESULTS: 17 patients had malignant diseases and 10 patients had benign diseases. Depending on the observer, the sensitivity, specificity, positive predictive value and negative predictive value of MRI varied between 88-94%, 50-80%, 75-89% and 71-89% respectively. Sensitivities, specificities, positive predictive values and negative predictive values of PET/CT were 73%, 56%, 73% and 56% respectively. The diagnostic accuracy of MR for the differential diagnosis of pancreatic lesions was 74-89%, compared with 67% for PET/CT. The weighted Cohen's kappa coefficient was 0.47 at MR and 0.53 at PET/CT. CONCLUSION: MRI achieved higher sensitivity and specificity in the differential diagnosis of pancreatic lesions.